| Week | Date | Rank | Rec | Points | FPV | CP | Last Week |
|---|---|---|---|---|---|---|---|
| Pre | Sep 11 | NR | 0-0 | 0 | 0 | DNP | |
| 1 | Sep 19 | 16 | 1-0 | 31 | 0 | ||
| 2 | Sep 26 | 19 | 2-0 | 24 | 0 | ||
| 3 | Oct 3 | 11 | 3-0 | 63 | 0 | ||
| 4 | Oct 10 | 6 | 4-0 | 176 | 0 | ||
| 5 | Oct 17 | 5 | 5-0 | 279 | 0 | ||
| 6 | Oct 24 | 5 | 6-0 | 283 | 0 | ||
| 7 | Oct 31 | 2 | 7-0 | 359 | 0 | ||
| 8 | Nov 7 | 2 | 8-0 | 387 | 4 | ||
| 9 | Nov 14 | 1 | 9-0 | 457 | 34 | W 41-19 at Oklahoma | |
| 10 | Nov 21 | 5 | 9-1 | 241 | 0 | L 23-7 vs Kansas | |
| Final | Nov 28 | 5 | 9-1 | 253 | 0 |
Note: Missouri's ranking in the final 1961 poll has been changed to unranked after the original AP wire story and poll was revisited and confirmed across several newspapers.